gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD20 on B cells and kills via Fc-mediated ADCC (enhanced FcγRIIIa engagement; also ADCP) and type II antibody–induced direct cell death/caspase-independent apoptosis of CD20+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type II anti-CD20; induces direct cell death and ADCC
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06656234
disease_id_num_tar_ref
252
drug_id_num_tar_ref
712