gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Therapeutic vaccination induces HPV16 E7–specific CD8+ T cells that recognize E7 peptides on MHC I of tumor/infected cells and kill them via perforin/granzyme (and Fas–FasL) cytotoxicity.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
HPV16 genotype-specific; presented as MHC class I/II peptides
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05829629
disease_id_num_tar_ref
2912
drug_id_num_tar_ref
7783