gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells bind CD19 on target cells, triggering T-cell activation and perforin/granzyme-mediated killing (apoptosis/lysis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-lineage surface marker; dual-target CAR (either antigen can trigger activation)
trial_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT07139509
disease_id_num_tar_ref
2913
drug_id_num_tar_ref
7784