gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccine primes HPV16 E6–specific CD8+ T cells that recognize E6 peptides on MHC I of tumor cells and kill them via CTL mechanisms (perforin/granzyme), aided by CD4+ T-cell help.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
HPV16 genotype; viral oncoprotein expressed by tumor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06223568
disease_id_num_tar_ref
2950
drug_id_num_tar_ref
7888