gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Vaccine expresses HPV16 E7, priming HPV16 E7–specific CD8+ T cells that recognize E7 peptides on MHC I and lyse tumor cells via perforin/granzyme (with possible antibody-mediated effects).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
HPV16 genotype; viral oncoprotein expressed by tumor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06223568
disease_id_num_tar_ref
2950
drug_id_num_tar_ref
7888