gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Engineered TCR-T cells recognize HPV E6/E7 peptide–HLA I complexes on tumor cells and kill them via cytotoxic T-cell effector functions (perforin/granzyme release and Fas–FasL–mediated apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
TCR recognizes a peptide–MHC class I (HLA-restricted) complex; specific allele/epitope not specified in trial
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06544720
disease_id_num_tar_ref
2955
drug_id_num_tar_ref
7900