gene_symbol
CD2
hgnc_id
HGNC:1639
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD2 IgG1 binds CD2 on T/NK cells and triggers Fc-dependent ADCC and complement-mediated lysis (CDC), depleting CD2+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface receptor on T and NK cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05900401
disease_id_num_tar_ref
2983
drug_id_num_tar_ref
7996