gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize CD20 on B cells, triggering CD3ζ signaling with 4-1BB costimulation and inducing cytolysis via perforin/granzyme (and Fas–FasL), killing CD20-positive cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
bispecific CAR target
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05800977
disease_id_num_tar_ref
2992
drug_id_num_tar_ref
8016