gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BCMA-targeted CAR T cells recognize BCMA on target cells and kill them via T-cell cytotoxicity, primarily perforin/granzyme-mediated lysis after CAR activation.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Dual-epitope binding to BCMA via two VHH domains
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06623630
disease_id_num_tar_ref
2995
drug_id_num_tar_ref
8023