gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR-T cells bind BCMA on target cells, activating cytotoxic T-cell responses that kill targets via perforin/granzyme-mediated apoptosis (and Fas/FasL).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface TNFR superfamily member expressed on plasma cells/myeloma
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06691685
disease_id_num_tar_ref
3002
drug_id_num_tar_ref
8055