gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
AZD5492 bridges CD20 on B cells with CD3/CD8 on CD8+ T cells, forming an immune synapse that activates TCR signaling and triggers perforin/granzyme-mediated killing of CD20+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06542250
disease_id_num_tar_ref
3019
drug_id_num_tar_ref
8104