gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
AZD5492 bridges CD8/CD3 on T cells to CD20 on B cells, activating T cells to release perforin/granzyme and kill CD20+ B cells; CD8+ T cells are not killed but serve as effectors.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell co-receptor on CD8+ T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06542250
disease_id_num_tar_ref
3019
drug_id_num_tar_ref
8104