gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19-directed CAR T cells recognize CD19 on target cells and kill them via T-cell effector mechanisms (perforin/granzyme-mediated lysis and death-receptor apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface B-cell antigen; HLA-independent CAR binding
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05809284
disease_id_num_tar_ref
3026
drug_id_num_tar_ref
8121