gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
BiTE antibody bridges BCMA on target cells and CD3 on T cells, forming an immunologic synapse that activates T-cell killing via perforin/granzyme-mediated cytotoxicity and cytokine release against BCMA+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06745687
disease_id_num_tar_ref
3032
drug_id_num_tar_ref
8137