gene_symbol
IL2RB
hgnc_id
HGNC:6009
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
These CAR T cells recognize GD2, not IL‑15Rβ; they kill GD2-positive cells via CAR-activated T-cell cytotoxicity (perforin/granzyme), while IL‑15Rβ-expressing cells are not targeted.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
IL-15 receptor component (shared IL-2/15Rβ)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05620342
disease_id_num_tar_ref
3042
drug_id_num_tar_ref
8168