gene_symbol
IL2RG
hgnc_id
HGNC:6010
binding_type
receptor ligand recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Killing is directed at GD2-positive cells via CAR-mediated T-cell cytotoxicity (perforin/granzyme). The common gamma chain is part of IL-15 receptor signaling on T cells and is not a cytotoxic target.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
IL-15 receptor component (common γ chain)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05620342
disease_id_num_tar_ref
3042
drug_id_num_tar_ref
8168