gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD20 on B cells and triggers complement-dependent cytotoxicity and Fc-mediated ADCC; cross-linking can also induce apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type I anti-CD20 mAb; binds large extracellular loop
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06356129
disease_id_num_tar_ref
22
drug_id_num_tar_ref
53