gene_symbol
FCRL5
hgnc_id
HGNC:18508
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-FCRL5 CAR T cells bind FCRL5 on target cells, triggering TCR/CD3zeta signaling and cytolytic killing via perforin/granzyme (and Fas/FasL)–mediated apoptosis of FCRL5+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
surface receptor on B-lineage cells; dual-targeted CAR scFv binding
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06759181
disease_id_num_tar_ref
3056
drug_id_num_tar_ref
8205