gene_symbol
ROR1
hgnc_id
HGNC:10256
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The NK cell engager binds ROR1 on tumor cells and CD16 on NK cells, bridging and activating NK cells to induce ADCC and perforin–granzyme–mediated lysis of ROR1-positive cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Tumor cell surface receptor tyrosine kinase-like orphan receptor 1
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06273852
disease_id_num_tar_ref
3087
drug_id_num_tar_ref
8279