gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD19 CAR-T cells bind CD19 on target B cells, triggering T-cell activation and cytotoxic killing via perforin/granzyme release and death receptor pathways, causing on‑target lysis of CD19+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
B-cell surface antigen targeted by CAR scFv
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06101381
disease_id_num_tar_ref
3090
drug_id_num_tar_ref
8285