gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize CD19 on target cells, activate, and kill via perforin/granzyme-mediated cytolysis leading to apoptosis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Co-targeted in dual CAR construct (CD19/CD22)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06911710
disease_id_num_tar_ref
3100
drug_id_num_tar_ref
8319