gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binds CD20 on B cells and induces killing via enhanced Fc gamma RIIIa–mediated ADCC by immune effectors, complement-dependent cytotoxicity (CDC), and direct caspase-independent cell death.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Type II epitope on CD20
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06073821
disease_id_num_tar_ref
3102
drug_id_num_tar_ref
8328