gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Teclistamab bridges CD3 on T cells to BCMA on target cells, forming an immune synapse and triggering T‑cell–mediated killing via perforin/granzyme-induced apoptosis of BCMA+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
membrane receptor on plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06588660
disease_id_num_tar_ref
3114
drug_id_num_tar_ref
8353