gene_symbol
CD38
hgnc_id
HGNC:1667
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Binding of daratumumab to CD38 on cells triggers antibody-mediated killing via ADCC, CDC, ADCP, and can induce apoptosis of CD38+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface glycoprotein; ectoenzyme (NADase/ADP-ribosyl cyclase)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05654506
disease_id_num_tar_ref
3128
drug_id_num_tar_ref
8404