gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
TCR recognition of the neoantigen peptide–HLA-II complex on tumor cells activates the infused CTLs to kill the presenting cells via perforin/granzyme-mediated cytotoxicity.
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Multiple individualized TSA epitopes; CD4+ TCR recognition; MHC class II restricted
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06193759
disease_id_num_tar_ref
3137
drug_id_num_tar_ref
8428