gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR NK cells recognize CD19 on target cells and directly kill them via MHC-independent degranulation with perforin/granzyme-mediated apoptosis (and potentially death-receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CAR-mediated, MHC-independent recognition on B cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06464679
disease_id_num_tar_ref
3142
drug_id_num_tar_ref
8434