gene_symbol
PDGFRB
hgnc_id
HGNC:8804
binding_type
other
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Imatinib directly inhibits PDGFRB tyrosine kinase activity, suppressing downstream survival/proliferation signaling and inducing apoptosis in PDGFRB‑dependent cells (non–immune-mediated).
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT04808115
disease_id_num_tar_ref
281
drug_id_num_tar_ref
787