gene_symbol
CD33
hgnc_id
HGNC:1659
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CD33-specific CAR T cells bind CD33 on target cells and, upon CAR activation, kill them via perforin/granzyme-mediated cytotoxicity (antigen-dependent, HLA-independent).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06326021
disease_id_num_tar_ref
3236
drug_id_num_tar_ref
8684