gene_symbol
DLL3
hgnc_id
HGNC:2909
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific T‑cell engager binds DLL3 on tumor cells and CD3 on T cells, forming a cytolytic synapse; activated T cells release perforin and granzymes to lyse DLL3‑expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Tumor-associated surface antigen on neuroendocrine tumors (Notch ligand family)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05879978
disease_id_num_tar_ref
3286
drug_id_num_tar_ref
8829