gene_symbol
ROR1
hgnc_id
HGNC:10256
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-ROR1 CAR T cells bind ROR1 on target cells and, upon CAR activation, induce cytotoxicity via T-cell effector functions (perforin/granzyme release and death-receptor pathways).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface receptor; tumor-associated antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05748938
disease_id_num_tar_ref
3290
drug_id_num_tar_ref
8840