gene_symbol
KLK2
hgnc_id
HGNC:6363
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific antibody links CD3 on T cells to KLK2 on tumor cells, forming an immune synapse and activating T cells to kill KLK2+ cells via perforin/granzyme-mediated cytolysis.
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Tumor-associated antigen on prostate cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06095089
disease_id_num_tar_ref
3293
drug_id_num_tar_ref
8842