gene_symbol
FOLH1
hgnc_id
HGNC:3788
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The bispecific links CD28 on T cells to PSMA on tumor cells, providing CD28 costimulation that activates T cells and redirects them to kill PSMA+ cells via CTL-mediated cytotoxicity (e.g., perforin/granzyme).
enzyme_product
On
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
tumor-associated antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06095089
disease_id_num_tar_ref
3293
drug_id_num_tar_ref
8843