gene_symbol
CD28
hgnc_id
HGNC:1653
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
The bispecific binds CD28 on T cells to provide costimulation while engaging PSMA on tumor cells; activated T cells kill PSMA-positive tumor cells, not CD28-expressing cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell costimulatory receptor
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06095089
disease_id_num_tar_ref
3293
drug_id_num_tar_ref
8843