gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Engineered TCR T cells recognize the HPV16 peptide-HLA-A*02:01 complex on target cells and induce cytolysis via perforin/granzyme release (with additional Fas-FasL/cytokine-mediated apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide–MHC class I (HLA-A*02:01) complex on tumor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06505551
disease_id_num_tar_ref
3294
drug_id_num_tar_ref
8844