gene_symbol
ROR1
hgnc_id
HGNC:10256
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
ROR1-targeted CAR T cells recognize ROR1 on tumor cells and directly kill them via T-cell cytotoxicity (perforin/granzyme-mediated apoptosis and Fas/FasL).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
CAR-targeted tumor antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05694364
disease_id_num_tar_ref
3305
drug_id_num_tar_ref
8879