gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognize the myeloma-associated surface antigen via the CAR, activate, and directly kill antigen-expressing cells through perforin/granzyme-mediated cytotoxicity (and Fas–FasL apoptosis).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Trial registry does not specify the antigen(s); exclusion of prior GPRC5D/CD19-directed therapy suggests possible relevance but is not confirmed.
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06472479
disease_id_num_tar_ref
25
drug_id_num_tar_ref
63