gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Infused TILs recognize the patient-specific peptide–HLA complex via native TCRs and kill the presenting cell through perforin/granzyme-mediated cytotoxicity (and Fas/FasL apoptosis).
enzyme_product
Off
epitope
On
variant
On
isoform
Off
hla_specific
On
gated
Off
other_modifier
Recognized by native TCRs on TILs; presented on HLA class I and/or II on melanoma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06151847
disease_id_num_tar_ref
3361
drug_id_num_tar_ref
9076