gene_symbol
CD19
hgnc_id
HGNC:1633
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-CD19 CAR-T cells bind CD19 on target B-lineage cells and kill them via contact-dependent cytotoxicity (perforin/granzyme-mediated apoptosis and death-receptor pathways), leading to B-cell depletion.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface B-lineage antigen
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06792344
disease_id_num_tar_ref
3404
drug_id_num_tar_ref
9189