gene_symbol
GPRC5D
hgnc_id
HGNC:13310
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
CAR T cells recognizing GPRC5D bind the antigen and kill target cells via perforin/granzyme-mediated cytotoxicity after CAR activation.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
cell-surface orphan GPCR on malignant plasma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06333509
disease_id_num_tar_ref
3435
drug_id_num_tar_ref
9282