gene_symbol
STEAP1
hgnc_id
HGNC:11378
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
The ADC binds STEAP1 on tumor cells, is internalized, and releases an intracellular cytotoxic payload that kills STEAP1-expressing cells (e.g., via microtubule disruption or DNA damage).
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
Cell-surface antigen (Six-transmembrane epithelial antigen of the prostate 1)
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06710379
disease_id_num_tar_ref
3503
drug_id_num_tar_ref
9496