gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Rituximab binds CD20 on B cells and induces complement-dependent cytotoxicity (CDC), recruits FcγR+ effector cells for antibody-dependent cellular cytotoxicity/phagocytosis (ADCC/ADCP), and can trigger apoptosis of the target cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06737250
disease_id_num_tar_ref
3517
drug_id_num_tar_ref
9531