gene_symbol
CD3E
hgnc_id
HGNC:1674
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Linvoseltamab engages CD3ε on T cells to activate them and bridge to BCMA+ myeloma cells; the activated T cells kill BCMA-expressing tumor cells via perforin/granzyme. CD3ε-expressing T cells are not killed.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
T-cell receptor complex component
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06376526
disease_id_num_tar_ref
3524
drug_id_num_tar_ref
9549