Skip to main content
gene_symbol
TNFRSF17
hgnc_id
HGNC:11913
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Bispecific CAR T cells bind BCMA on target cells, triggering CD3ζ/costimulatory signaling and T‑cell activation, leading to perforin/granzyme- and death receptor–mediated killing of BCMA+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
tumor-associated cell-surface antigen
trial_id_tar_ref
nct_id_tar_ref
NCT06515262
disease_id_num_tar_ref
3532
drug_id_num_tar_ref
9573