gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Anti-GD2 IgG1 binds GD2 on tumor cells and triggers FcγR-mediated ADCC by NK cells/macrophages/granulocytes and complement-dependent cytotoxicity, leading to target-cell lysis.
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
glycolipid (ganglioside) antigen on neuroblastoma cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06528496
disease_id_num_tar_ref
3548
drug_id_num_tar_ref
9617