gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Therapeutic vaccine transduces APCs to present HPV16 E7, priming E7-specific CD8+ T cells. These CTLs recognize E7-derived peptides on MHC I of tumor cells and kill them via perforin/granzyme-mediated cytolysis.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
HPV16-specific viral antigen; peptides presented on MHC class I of tumor cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05108870
disease_id_num_tar_ref
3555
drug_id_num_tar_ref
9642