gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Adoptively transferred antigen-specific CTLs recognize the tumor antigen peptide presented by HLA class I via their native TCR and induce target-cell death via perforin/granzyme-mediated cytolysis (and Fas/FasL apoptosis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
TCR recognition of peptide–MHC class I complexes on pediatric solid tumor cells; specific TAAs not specified in the trial
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT07240207
disease_id_num_tar_ref
3596
drug_id_num_tar_ref
9775