gene_symbol
HLA-B
hgnc_id
HGNC:4932
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Adoptively transferred CTLs recognize the tumor peptide–HLA-B complex via their TCR and kill targets by perforin/granzyme-mediated apoptosis and death-receptor signaling (FasL/TRAIL).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Peptide–MHC complex recognized by endogenous TCR; patient- and antigen-specific; may include neoantigens
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06296056
disease_id_num_tar_ref
302
drug_id_num_tar_ref
863