gene_symbol
MS4A1
hgnc_id
HGNC:7315
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
DIRECT
cytotoxicity_mechanism
Glofitamab links CD3 on T cells to CD20 on target cells, forming an immune synapse and inducing T‑cell cytotoxicity (perforin/granzyme-mediated apoptosis, +/- Fas/FasL).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
Off
gated
Off
other_modifier
2:1 bispecific format includes two CD20-binding arms
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT05833763
disease_id_num_tar_ref
3625
drug_id_num_tar_ref
9851