gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
YES
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Dendritic-cell vaccination primes EBV-specific CD8+ T cells, which recognize EBV peptides presented on MHC I of EBV+ tumor cells and kill them via perforin/granzyme-mediated cytolysis (CTL-mediated lysis).
enzyme_product
Off
epitope
On
variant
Off
isoform
Off
hla_specific
On
gated
Off
other_modifier
Presented on MHC class I and II by autologous dendritic cells to activate EBV-specific CD8+ and CD4+ T cells
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06370026
disease_id_num_tar_ref
3639
drug_id_num_tar_ref
9887