gene_symbol
UNKNOWN
binding_type
antigen recognition
cytotoxicity
NO
cytotoxicity_type
INDIRECT
cytotoxicity_mechanism
Teclistamab binds CD3 on T cells to activate and bridge them to BCMA+ myeloma cells; the T cells then kill the BCMA-expressing tumor cells via perforin/granzyme, not the CD3+ cells.
enzyme_product
Off
epitope
Off
variant
Off
isoform
Off
hla_specific
Off
gated
Off
trial_id_tar_ref
drug_id_tar_ref
disease_id_tar_ref
nct_id_tar_ref
NCT06062537
disease_id_num_tar_ref
3640
drug_id_num_tar_ref
9888